Author

Akihiro Yamagchi

Juntendo University

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1

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Kei-ichi IshikawaiD· 1 shared Wado AkamatsuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperNeuroscience

Kei-ichi IshikawaORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintFeb 10, 2026

Modeling the pathological brain-gut axis in Parkinson's disease using human iPSC derived brain-intestinal assembloids

Akihiro Yamagchi, Kei-ichi Ishikawa, Wado Akamatsu

This study uses human iPSC-derived brain-intestinal assembloids to show synuclein propagation from brainstem to enteric neurons and identifies NRXN1-NLGN2 signaling as a key mediator.

DOI 10.64898/2026.02.07.704302

humanexperimental assay

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