The paper presents a high-quality chromosome-scale genome assembly for the American Shorthair domestic cat breed, improving upon previous fragmented assemblies.

Journal of Advanced Research · Oct 30, 2024Peer-reviewedGenomics

A chromosome-scale strawberry genome assembly of a Japanese variety, Reikou

Kenta Shirasawa, Hideki Hirakawa, Shinobu Nakayama, Shigemi Sasamoto, Hisano Tsuruoka, Chiharu Minami, Akiko Watanabe, Yoshie Kishida, Mitsuyo Kohara, Manabu Yamada, Tsunakazu Fujishiro, Akiko Komaki, Sachiko Isobe

This study presents a chromosome-scale genome assembly for the Japanese strawberry variety Reikou and identifies its likely progenitors as F. vesca and F. iinumae.

bioRxiv · Apr 23, 2021 · PreprintGenomics

Role of an atypical cadherin gene, Cdh23 in prepulse inhibition and its implication in schizophrenia

Shabeesh Balan, Tetsuo Ohnishi, Akiko Watanabe, Hisako Ohba, Yoshimi Iwayama, Manabu Toyoshima, Tomonori Hara, Yasuko Hisano, Yuki Miyasaka, Tomoko Toyota, Chie Shimamoto‐Mitsuyama, Motoko Maekawa, Shusuke Numata, Tetsuro Ohmori, Tomomi Shimogori, , Takeo Yoshikawa

The paper identifies a Cdh23 variant associated with prepulse inhibition and schizophrenia risk in mice and humans.

Schizophrenia Bulletin · Jan 14, 2021Peer-reviewedGenetics

Investigation of betaine as a novel psychotherapeutic for schizophrenia

Tetsuo Ohnishi, Shabeesh Balan, Manabu Toyoshima, Motoko Maekawa, Hisako Ohba, Akiko Watanabe, Yoshimi Iwayama, Yūkō Fujita, Yunfei Tan, Yasuko Hisano, Chie Shimamoto‐Mitsuyama, Yayoi Nozaki, Kayoko Esaki, Atsuko Nagaoka, Junya Matsumoto, , Takeo Yoshikawa

This study investigates betaine's role in schizophrenia using metabolomics and genetic approaches, finding it may alleviate oxidative stress and improve cognitive function in specific cases.

EBioMedicine · Jun 26, 2019Peer-reviewedNeuroscience