This study identifies senomorphic and senolytic agents that counteract UV-induced senescence in XP-derived melanocytes, reducing SASP gene expression and related pathway activation.

Stem Cell Research & Therapy · Oct 5, 2026Peer-reviewedCell Biology

AnAms1.0: A high-quality chromosome-scale assembly of a domestic cat Felis catus of American Shorthair breed

Yuki Matsumoto, Claire Chung, Sachiko Isobe, Mika Sakamoto, Xiao Lin, Ting‐Fung Chan, Hideki Hirakawa, Genki Ishihara, Hon‐Ming Lam, Shinobu Nakayama, Shigemi Sasamoto, Yasuhiro Tanizawa, Akiko Watanabe, Kei Watanabe, Masaru Yagura, , Yasukazu Nakamura

The paper presents a high-quality chromosome-scale genome assembly for the American Shorthair domestic cat breed, improving upon previous fragmented assemblies.

Journal of Advanced Research · Oct 30, 2024Peer-reviewedGenomics

A role for condensin-mediator interaction in mitotic chromosomal organization

Osamu Iwasaki, Sanki Tashiro, Claire Chung, Tomomi Hayashi, Hideki Tanizawa, Xuebing Wang, Shinya Ohta, Yūko Fujioka, Joseph Han, Gabrielle Tabor, Mikihiro Kawagoe, Ronen Marmorstein, Nobuo N. Noda, Ken-ichi Noma

This study identifies a condensin-mediator interaction in fission yeast that is essential for mitotic chromosomal organization and segregation.

bioRxiv · Jun 26, 2024 · PreprintGenomics

Accurate identification of structural variations from cancer samples

Le Li, Chenyang Hong, Jie Xu, Claire Chung, Alden King-Yung Leung, Delbert Almerick T. Boncan, Lixin Cheng, Kwok Wai Lo, Paul B.S. Lai, John Wong, Jingying Zhou, Alfred S.L. Cheng, Ting‐Fung Chan, Feng Yue, Kevin Yuk-Lap Yip

The paper introduces COMSV, a method for identifying structural variations in cancer samples, showing high sensitivity and specificity and detecting hundreds of novel SVs per sample.

Briefings in Bioinformatics · Nov 22, 2023Peer-reviewedGenomics

A Chromosome-level Assembly of the Japanese Eel Genome, Insights into Gene Duplication and Chromosomal Reorganization

Hongbo Wang, Hin Ting Wan, Bin Wu, Jianbo Jian, Alice Hoi-Man Ng, Claire Chung, Eugene Yui‐Ching Chow, Jizhou Zhang, Aol Wong, Keng Po Lai, Ting‐Fung Chan, Lu Zhang, Chris K.C. Wong

This paper presents a high-quality chromosome-level genome assembly of the Japanese eel and identifies gene duplication events and chromosomal reorganization linked to evolutionary adaptation.

GigaScience · Jan 1, 2022Peer-reviewedGenomics

Systematic selection of reference genes for normalization of circulating RNA transcripts in pregnant women based on RNA-seq data

Stephen S. C. Chim, Karen Ka-Wing Wong, Claire Chung, Stephanie K. W. Lam, Jamie Sui-Lam Kwok, Chit Ying Lai, Yvonne K. Y. Cheng, Shuk Yi Annie Hui, Meng Meng, Oi Ka Chan, Stephen Kwok‐Wing Tsui, Keun-Young Lee, Ting‐Fung Chan, Tak-Yeung Leung

The paper identifies a panel of stably expressed genes for normalizing circulating RNA transcripts in maternal blood using RNA-seq data from preterm labor samples.

International Journal of Molecular Sciences · Aug 4, 2017Peer-reviewedGenomics