Author
Sachiko Isobe
Kazusa DNA Research InstituteORCID 0000-0002-9555-5054Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2026 · peak 9/yrCo-Author Collaboration Network
10 top collaborators · 23 mutual co-author links44 papers
Recent·Most cited
- Plant BiologybioRxivPreprintDOI 10.64898/2026.10.05.756862
- GeneticsbioRxivPreprint
A naturally occurring frameshift mutation in the UNUSUAL FLORAL ORGANS gene associated with the marimo floral phenotype in gerbera
Taro Hattori, Riki Shimada, Moe Nagakura…·Akiyoshi Tominaga
The paper identifies a frameshift mutation in the UFO gene causing the marimo floral phenotype in gerbera by disrupting the LFY-UFO regulatory module.
DOI 10.64898/2026.08.09.743735 - GenomicsGenome ResearchPeer-reviewed
Tracing genome size dynamics in sharks and rays with inclusive sequence analysis by the Squalomix Consortium
Shigehiro Kuraku, Yawako W. Kawaguchi, Taiki Niwa…·Akane Kawaguchi
The paper presents whole genome sequences of two elasmobranchs, analyzing genome size dynamics and genomic architecture, revealing correlations between chromosome size, repetitive elements, and gene duplication patterns.
- GeneticsMolecular BreedingPeer-reviewed
Progeny-based genomic selection reveals untapped genetic potential in an underutilized medicinal plant, Perilla frutescens
S. Kinoshita, Kengo Sakurai, Takahiro Tsusaka…·Hiroyoshi Iwata
This study applies genomic selection to improve medicinal compounds in red perilla, showing that GS-based crosses outperform phenotypic selection in target compound levels.
DOI 10.1007/s11032-026-01700-6 - Evolutionary BiologyPlant BiologyPeer-reviewed
Molecular evolution of terpene synthase underlying the diversification of isoprene emission in Fagaceae
Yuka Ikezaki, Shuichi N. Kudo, Nakata Taichi…·Akiko Satake
The paper investigates the molecular evolution of terpene synthase genes in Fagaceae, revealing convergent evolution of isoprene synthase activity in two lineages within subgenus Quercus.
- Plant BiologyThe Plant GenomePeer-reviewed
Genomic Architecture of the Resistance to Phytophthora Cactorum 2 (RPc2) Locus in Strawberry (Fragaria x ananassa)
Hyeondae Han, Youngjae Oh, Yoon Jeong Jang…·Seonghee Lee
This study fine-maps the RPc2 resistance locus in strawberries to 546 kb, identifies candidate genes, and reveals the genetic architecture and haplotype distribution of resistance to Phytophthora crown rot.
7 citationstop 2% - Plant BiologyDNA ResearchPeer-reviewed
Chromosome-level genome assembly of the gerbera (Gerbera hybrida) using HiFi long-read and Hi-C technologies
Yuta Aoyagi Blue, Riki Shimada, Hideki Hirakawa…·Akiyoshi Tominaga
The paper presents a chromosome-level genome assembly of Gerbera hybrida using HiFi and Hi-C technologies, providing annotated nuclear, mitochondrial, and chloroplast genomes.
2 citationstop 5% - Evolutionary BiologyeLifePeer-reviewed
Evolution of gene expression in seasonal environments
Shuichi N. Kudo, Yuka Ikezaki, Junko Kusumi…·Akiko Satake
This study compares seasonal gene expression across four tree species, finding conserved winter rhythms and divergent summer patterns, suggesting a shared molecular calendar in winter.
1 citation - Plant BiologySensorsPeer-reviewed
CLCFM3: An advanced photogrammetry algorithm for high-precision plant 3D modeling
Atsushi Hayashi, Nobuo Kochi, Kunihiro Kodama…·Takanari Tanabata
This paper introduces CLCFM3, a photogrammetry algorithm for high-precision 3D plant modeling, addressing occlusion and noise in complex plant structures.
3 citations - Plant BiologybioRxivPreprint
Heat stress negatively affects betalain biosynthesis in Amaranthus tricolor through down-regulation of CYP76AD1 and 5GT
Ya‐Ping Lin, Tomomi Ohokubo, Akito Nashiki…·Ken Hoshikawa
The paper identifies CYP76AD1 and 5GT as heat stress-downregulated genes affecting betalain biosynthesis in Amaranthus tricolor.
DOI 10.1101/2025.03.05.641739 - BioinformaticsbioRxivPreprint
Optimization of crossing strategy based on the usefulness criterion in inter-population crosses considering different genetic effects among populations
S. Kinoshita, Kengo Sakurai, Kosuke Hamazaki…·Hiroyoshi Iwata
This study proposes a method to select optimal cross pairs in inter-population crosses by considering genetic effects across populations, showing increased genetic gains in multiple traits.
DOI 10.1101/2025.01.21.634020 - Plant BiologyIkushugaku zasshiPeer-reviewed
Frame-shift mutation of InCO might cause early flowering of Japanese morning glory and might have contributed to northward expansion
Hiroaki Katsuyama, Takuro Ito, Kyousuke Ezura…·Tsutomu Kuboyama
The paper identifies a frame-shift mutation in InCO causing early flowering in Japanese morning glory, which may have facilitated its northward expansion into temperate Asia.
2 citations - Plant BiologyNaturePeer-reviewed
Adaptive diversification through structural variation in barley
Murukarthick Jayakodi, Qiongxian Lu, Hélène Pidon…·Nils Stein
This study presents a barley pangenome revealing structural variation linked to traits like disease resistance and plant architecture, highlighting its role in adaptive evolution.
183 citationstop 1% - GenomicsJournal of Advanced ResearchPeer-reviewed
AnAms1.0: A high-quality chromosome-scale assembly of a domestic cat Felis catus of American Shorthair breed
Yuki Matsumoto, Claire Chung, Sachiko Isobe…·Yasukazu Nakamura
The paper presents a high-quality chromosome-scale genome assembly for the American Shorthair domestic cat breed, improving upon previous fragmented assemblies.
10 citations - GenomicsbioRxivPreprint
Near-complete telomere-to-telomere de novo genome assemblies of Egyptian clover (Trifolium alexandrinum)
Mitsuhiko P. Sato, Ramadan Ahmed Arafa, Mohamed Rakha…·Kenta Shirasawa
The paper presents near-complete telomere-to-telomere genome assemblies for two Egyptian clover cultivars using long-read sequencing and a novel gap-targeted method.
DOI 10.1101/2024.07.04.602140 - GeneticsbioRxivPreprint
Quantifying Forest Biomass and Genetic Contribution using Light Detection and Ranging
Haruka Sano, Naoko Miura, Minoru Inamori…·Hiroyoshi Iwata
This study uses LiDAR to measure tree traits and assess their heritability in larch trees, finding backpack LiDAR provides more accurate DBH estimates than UAV LiDAR.
DOI 10.1101/2024.07.03.601985 - BioinformaticsbioRxivPreprint
Hayai-Annotation v3.0: A functional gene prediction tool that integrates orthologs and gene ontology for network analysis
Hayai-Annotation v3 provides a tool for functional gene prediction using orthologs and gene ontology, enhancing cross-species gene function analysis and visualization.
DOI 10.1101/2024.06.05.597500 - GeneticsbioRxivPreprint
B chromosome and its non-Mendelian inheritance in Atractylodes lancea
Kazuya Hara, Shinji Kikuchi, Misaki Inoue…·Sachiko Isobe
This study identifies B chromosomes in Atractylodes lancea and shows their non-Mendelian inheritance from female parents.
DOI 10.1101/2024.05.27.595828 - GenomicsGenesPeer-reviewed
Assessing the potential for genome-assisted breeding in red perilla using quantitative trait locus analysis and genomic prediction
S. Kinoshita, Kengo Sakurai, Kosuke Hamazaki…·Hiroyoshi Iwata
This study evaluates genomic selection and marker-assisted selection for improving medicinal compound production in red perilla using quantitative trait locus analysis and genomic prediction.
- GenomicsJournal of Forest ResearchPeer-reviewed
Haplotype-resolved de novo genome assemblies of four coniferous tree species
Kenta Shirasawa, Kentaro Mishima, Hideki Hirakawa…·Makoto Takahashi
This study generates high-quality haplotype-resolved genome assemblies for four coniferous tree species using long-read sequencing, revealing high heterozygosity and facilitating genetic and breeding research.
- GenomicsDNA ResearchPeer-reviewed
Telomere-to-telomere genome assembly of an allotetraploid pernicious weed, Echinochloa phyllopogon
Mitsuhiko P. Sato, Satoshi Iwakami, Kanade Fukunishi…·Kenta Shirasawa
The paper presents a telomere-to-telomere genome assembly of Echinochloa phyllopogon, revealing structural differences between its A and B genomes and their implications for herbicide resistance.
- BioinformaticsbioRxivPreprint
Benchmarking Hayai-Annotation Plants: A Re-evaluation Using Standard Evaluation Metrics
Andrea Ghelfi, Kenta Shirasawa, Sachiko Isobe
This paper benchmarks Hayai-Annotation Plants against Blast2GO and TRAPID using standard metrics, finding it outperforms both in gene ontology annotation for Arabidopsis thaliana.
- GenomicsbioRxivPreprint
Haploid-resolved and chromosome-scale genome assembly in Citrus unshiu and its parental species, C. nobilis and C. kinokuni
Sachiko Isobe, Hiroyoshi Fujii, Kenta Shirasawa…·Takehiko Shimada
The paper generates chromosome-scale and haploid-resolved genome assemblies for Citrus unshiu and its parental species using long-read sequencing and Hi-C, revealing structural differences and polymorphism variations.
- GenomicsDNA ResearchPeer-reviewed
Telomere-to-telomere genome assembly of matsutake (Tricholoma matsutake)
Hiroyuki Kurokochi, Naoyuki Tajima, Mitsuhiko P. Sato…·Kenta Shirasawa
The paper presents the first telomere-to-telomere genome assembly of matsutake, revealing genomic features and variations that provide a reference for future genetic and conservation studies.
- GenomicsbioRxivPreprint
Haploid-resolved and chromosome-scale genome assembly in hexa-autoploid sweetpotato (Ipomoea batatas (L.) Lam)
Ung-Han Yoon, Qinghe Cao, Kenta Shirasawa…·Sachiko Isobe
The paper presents a chromosome-scale genome assembly for hexaploid sweetpotato, identifying genes involved in starch, anthocyanin, and carotenoid pathways.
- GenomicsDNA ResearchPeer-reviewed
Chromosome-scale genome assembly of a Japanese chili pepper landrace, Capsicum annuum 'Takanotsume'
Kenta Shirasawa, Munetaka Hosokawa, Yasuo Yasui…·Sachiko Isobe
This study presents a chromosome-scale genome assembly of the Japanese chili pepper landrace Capsicum annuum 'Takanotsume' using long-read sequencing and optical mapping, revealing genome structure variations compared to related species.
- GenomicsDNA ResearchPeer-reviewed
De novo whole-genome assembly in interspecific hybrid table grape, ‘Shine Muscat’
Kenta Shirasawa, Hideki Hirakawa, Akifumi Azuma…·Sachiko Isobe
This paper presents the first genome sequence of the interspecific hybrid grape cultivar Shine Muscat, providing insights into its genome structure and gene content.
30 citations - GenomicsDNA ResearchPeer-reviewed
Chromosome-scale haplotype-phased genome assemblies of the male and female lines of wild asparagus (Asparagus kiusianus), a dioecious plant species
Kenta Shirasawa, Saki Ueta, Kyoko Murakami…·Sachiko Isobe
This study presents chromosome-scale haplotype-phased genome assemblies for male and female lines of wild asparagus, revealing genetic differences and potential sex determination mechanisms.
- GenomicsDNA ResearchPeer-reviewed
Genome sequencing and analysis of two early-flowering cherry (Cerasus x kanzakura) varieties, 'Kawazu-zakura' and 'Atami-zakura'
Kenta Shirasawa, Akihiro Itai, Sachiko Isobe
This study sequenced and analyzed the genomes of two early-flowering cherry varieties to identify genetic factors contributing to their early-flowering phenotype.
13 citations - GenomicsGigabytePeer-reviewed
A Chromosome-scale draft genome sequence of horsegram (Macrotyloma uniflorum)
Kenta Shirasawa, Rakesh Kumar Chahota, Hideki Hirakawa…·Sachiko Isobe
The paper generates and analyzes a draft genome sequence for horsegram, identifying specific genes and genome structure similarities with other legumes.