Author

Alan Mertens

RWTH Aachen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Gigly G. Del’hayeiD· 1 shared Jessie NeuckermansiD· 1 shared Joery De KockiD· 1 shared Karina Tretowicz· 1 shared Liesbeth DesmetiD· 1 shared Nina Stefanie SalviiD· 1 shared Sien LequeueiD· 1 shared Tamara VanhaeckeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Gigly G. Del’hayeORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Tuning inhibitor susceptibility of human 4-hydroxyphenylpyruvate dioxygenase to rescue tyrosine catabolism in the presence of β-triketones

Jessie Neuckermans, Alan Mertens, Sien Lequeue, Nina Stefanie Salvi, Liesbeth Desmet, Gigly G. Del’haye, Karina Tretowicz, Tamara Vanhaecke, Ulrich Schwaneberg, Joery De Kock

This study engineers HPD variants with enhanced NTBC tolerance to restore tyrosine metabolism while maintaining catalytic activity and MHC-II binding properties.

bioRxiv · Oct 23, 2026 · PreprintBiochemistry