Pharmacology & ToxicologyACS Pharmacology & Translational SciencePeer-reviewed
Comprehensive Characterization of BTK Inhibitor Specificity, Potency, and Biological Effects: Insights into Covalent and Non-covalent Mechanistic Signatures
Antonia C. Darragh, Andrew M. Hanna, Justin H. Lipner…·Mirza Jahic
This paper characterizes the potency, selectivity, and biological effects of fifteen BTK inhibitors, revealing differences between covalent and non-covalent inhibitors in binding affinity and off-target effects.
8 citations