Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons
Wei Liu, Rupendra Shrestha, Albert Lowe, Xusheng Zhang, Ludovic Spaeth
The paper reports the self-formation of human telencephalon-eye organoids with concentric tissue zones and directional RGC axon growth, identifying key molecular and cellular mechanisms.
eLife · Sep 4, 2023Peer-reviewedDevelopmental Biology