Optopharmacological tools for precise spatiotemporal control of oxytocin signaling in the central nervous system and periphery
Ismail A. Ahmed, Jing-Jing Liu, Krystyna A. Gieniec, Chloe J. Bair-Marshall, Ayomiposi B. Adewakun, Belinda E. Hetzler, Christopher J. Arp, Latika Khatri, Gilles Claude Vanwalleghem, Alec Seidenberg, Pamela Cowin, Dirk Trauner, Moses V. Chao, Felicity M. Davis, Richard W. Tsien, Robert C. Froemke
This paper develops and validates caged oxytocin analogs that can be activated with light to precisely control oxytocin signaling in the brain and peripheral tissues.
bioRxiv · Nov 10, 2022 · PreprintNeuroscience