Robert C. Froemke

The paper identifies a collicular-hypothalamic pathway that signals social visual awareness to the oxytocin system, enhancing pup retrieval behavior in mice.

The paper shows that astrocytes mediate a positive feedback loop for oxytocin by upregulating its expression through retinoic acid synthesis.

The paper shows microglia support neuronal protein synthesis by coordinating metabolic coupling in response to increased demand from motor tasks.

The paper investigates how cortical neurons represent acoustic and electrical cochlear implant stimulation in deafened rats, finding distinct spatio-temporal response profiles.

This study tracks how auditory cortex neurons in mice develop functional responses to sound over time, showing changes in tuning and frequency representation.

This study maps the spatiotemporal dynamics of de novo protein synthesis in mice brains after auditory threat conditioning using a novel labelling technique.

This study analyzes LC neuron firing patterns across species and biological factors, revealing diverse activity patterns and subregions enriched for specific factors and disease models.

This study uses TUS and calcium imaging in awake mice to show focal effects on cortical activity and proposes a circuit model explaining these effects.

This study shows that vagus nerve stimulation enhances perceptual learning in mice by activating the central cholinergic system during auditory tasks.

This study shows that integrin-deficient T-cell leukemia accumulates in the CNS and proliferates faster, suggesting integrins normally restrict T-ALL growth there, and integrin blockade could enhance chemotherapy.

The paper identifies a neural circuit in mice that links infant cries to oxytocin neuron activation, showing how auditory cues influence maternal behavior through thalamic input.

The paper shows maternal experience enhances midbrain integration of multi-syllable pup calls while suppressing subcortical excitation.

This study shows that TDP-43 accumulation in astrocytes impairs memory by altering antiviral pathways and chemokine signaling between astrocytes and neurons.

The paper shows that experienced female mice can improve maternal-infant survival by assisting in caregiving and parturition, particularly for mice lacking the oxytocin receptor.

This study shows that locus coeruleus activity predicts and enhances cochlear implant performance in deafened rats through behavioral and neural responses.

This paper develops and validates caged oxytocin analogs that can be activated with light to precisely control oxytocin signaling in the brain and peripheral tissues.

The paper investigates inhibitory plasticity in mouse auditory cortex, finding that SST+ interneuron inputs show the most potentiation and contribute to decision accuracy under noise.

This study shows that oxytocin reduces microglial activation and improves memory in Alzheimer's disease mouse models.

The paper shows that diverse neural response profiles in auditory cortex arise from synaptic plasticity and contribute differently to task performance.

The paper develops a system combining 3D videography and deep learning to automatically track and analyze social interactions in mice, revealing multiplexed social receptive fields in the barrel cortex.

The paper shows how heterosynaptic plasticity calibrates excitatory and inhibitory inputs onto pyramidal neurons to achieve excitatory-inhibitory balance.

The paper shows that maternal behavior in mice arises from innate auditory cortex sensitivity combined with experience-dependent plasticity, enabling reliable pup retrieval.

The paper shows that social interactions between mother mice and virgin mice activate oxytocin neurons, enabling the virgins to acquire maternal behavior through social transmission.

The paper identifies task-relevant information in nominally non-responsive neurons using a spike-timing-based algorithm in behaving rats.

The paper shows that knowledge acquisition and expression can be dissociated by using probe trials without reinforcement, revealing that performance variability stems from testing context rather than inherent ability.