The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture
Paula P. Navarro, Andrea Vettiger, Roman Hajdu, Virly Y. Ananda, Alejandro Lopez-Tavares, Ernst W. Schmid, Johannes C. Walter, Martin Loose, Luke H. Chao, Thomas G. Bernhardt
This study identifies PBP1b's specialized role in E. coli division site fortification against osmotic rupture, showing it functions independently of LpoB and requires an extended N-terminus for recruitment by FtsA.
bioRxiv · Apr 2, 2025 · PreprintMicrobiology