A Bioactive Phospholipid Promotes Rapid Progenitor Lung Progenitor Activation via AP-1
Alena Klochova, Aaron I. Weiner, Kentaro Hata, Nicolas P. Holcomb, Sara Kass-Gergi, Meryl Mendoza, Evelyn A. Martinez, Diana M Abraham, Melanie Y Staszewski, Michael M. Maiden, Jeremy B. Katzen, Andrew E. Vaughan
This study identifies lysophosphatidic acid (LPA) as a key bioactive lipid that promotes alveolar type 2 cell progenitor activation via AP-1 transcription factors during lung regeneration.
bioRxiv · Jul 29, 2026 · PreprintCell Biology