JAK2 is highly expressed by cyst-lining cells and regulates cystogenesis.
Foteini Patera, Alex Cudzich-Mardy, Zhi Huang, Maria Fragiadaki
This study investigates JAK2's role in cystogenesis using a murine model, finding that JAK2 inhibition reduces cystic growth in vitro.
bioRxiv · Aug 21, 2018 · PreprintCell Biology