Ankhd1 enhances polycystic kidney disease development via promoting proliferation and fibrosis.
Foteini Patera, Guillaume M. Hautbergue, Patricia D. Wilson, Paul Charles Evans, Albert C.M. Ong, Maria Fragiadaki
This study identifies ANKHD1 as a driver of ADPKD by promoting proliferation and fibrosis, showing its inhibition could be therapeutically beneficial.
bioRxiv · Mar 4, 2020 · PreprintMolecular Biology