Organelle interdependencies underlie the collapse of eukaryotic intracellular organization during cell death and aging
Athanasios Litsios, Dara S. Lo, Arthur Fischbach, Helena Friesen, Alex Daiejavad, Nil Sahin, Myra Paz David Masinas, Thuy Nguyen, Carles Pons, Jing Hou, Quaid Morris, Thomas Nyström, Charles M. Boone, Brenda Andrews
The paper uses high-content imaging and machine learning to study how perturbing essential genes affects subcellular organization in yeast, revealing cascade effects and a threshold for cell death.
bioRxiv · Aug 28, 2026 · PreprintGenomics