Minocycline enhances antimicrobial activity of unpolarized macrophages against Acinetobacter baumannii while reducing the inflammatory response
Alberto Daniel Guerra, Cecilia F. Volk, Alex Peterson-Weber, Jason M. Peters, George Sakoulas, John‐Demian Sauer, Warren E. Rose
This study shows minocycline enhances macrophage killing of Acinetobacter baumannii and reduces inflammation in a dose-dependent manner, suggesting improved in vivo efficacy.
bioRxiv · Sep 27, 2024 · PreprintImmunology