Causal identification of single-cell experimental perturbation effects with CINEMA-OT
Mingze Dong, Bao Wang, Jessica Wei, Antonio H. de O. Fonseca, Curtis J. Perry, Alexander Frey, Feriel Ouerghi, Ellen F. Foxman, Jeffrey Joseph Ishizuka, Rahul M. Dhodapkar, David van Dijk
CINEMA-OT identifies causal effects of single-cell perturbations by separating confounding variation, outperforming existing methods on simulated and real datasets.
Nature Methods · Nov 1, 2023Peer-reviewedBioinformatics