Feriel Ouerghi

The paper uses patient tumor samples to identify lineage- and context-specific mechanisms of innate immune resistance through perturbational single-cell RNA sequencing.

This paper shows that the likelihood ratios from IBDGem test a null hypothesis different from the traditional forensic one, potentially overestimating evidence strength for identity.

CINEMA-OT identifies causal effects of single-cell perturbations by separating confounding variation, outperforming existing methods on simulated and real datasets.