Selective reduction of KCNA4 in vulnerable glutamatergic-serotonin neurons of the dorsal raphe nucleus in Alzheimers Disease
Louis John Kolling, Nagalakshmi Balasubramanian, Shafa Ismail, Alexander James Feller, Jessica Marie Hunter Alberhasky, Ruixiang Wang, Luke Jennings, Marco M. Hefti, Catherine Anne Marcinkiewcz
The paper investigates how selective reduction of KCNA4 in 5HT/glut neurons of the dorsal raphe nucleus contributes to tau pathology and depressive-like behaviors in Alzheimer's disease.
Alzheimer s & Dementia · May 1, 2026Peer-reviewedNeuroscience