Nagalakshmi Balasubramanian

The paper investigates how selective reduction of KCNA4 in 5HT/glut neurons of the dorsal raphe nucleus contributes to tau pathology and depressive-like behaviors in Alzheimer's disease.

This study shows that adolescent social isolation promotes tau spread in raphe nuclei, causing depression-like and pain-related symptoms in Alzheimer's disease.

This study investigates the role of CART peptide in serotonergic function and anxiety by demonstrating its anxiogenic effects and inhibitory impact on 5HTDRN neurons in mice.

The paper identifies tau pathology in the dorsal raphe nucleus as a potential early indicator of Alzheimer's disease, linked to behavioral changes and neuroinflammation.

This study identifies the lateral septum as a key circuit involved in ketamine-induced social deficits, showing that its hypoactivation contributes to schizophrenia-like behaviors.

This paper shows that adolescent isolation in mice leads to type 2 diabetes and identifies a serotonin/GLP-1 neural circuit as a potential target for understanding the link between social isolation and diabetes.

This study shows chronic alcohol exposure increases social avoidance in male mice by enhancing serotonergic inputs to the nucleus accumbens, which inhibits dopamine release and reduces social motivation.

The paper examines how chronic ethanol exposure affects ACE2 and TMPRSS2 expression in specific brain regions, suggesting increased vulnerability to SARS-CoV-2 neuroinvasion.