ZMYND11 Restrains KMT2A to Enable a Neuronal Developmental Program
Alexander W. Greben, Xiaoli Wu, Josephine E. Robb, Ian R. Vogel, Lisa Traunmüller, Sebastian Krüttner, Kara A. Fulton, Migue Van Louis Darcera, Eric C. Griffith, Michael E. Greenberg
This study shows that ZMYND11 inhibits KMT2A to regulate neuronal development, and a mutation in ZMYND11 disrupts this interaction, leading to developmental and behavioral abnormalities.
bioRxiv · Oct 31, 2025 · PreprintNeuroscience