High-density Lipoprotein Inspired Lipid Nanoparticles for Systemic RNA delivery to the Brain
Zunkai Xu, Kiruba Shalin, Vy Do, Alexander Yan, Jingjing Gao
This study develops HDL-inspired lipid nanoparticles for targeted RNA delivery to the brain, showing improved BBB transport and cell-type-specific therapeutic effects in mouse models.
bioRxiv · Jun 1, 2026 · PreprintBioengineering