The Hexosamine Biosynthetic Pathway alters the cytoskeleton to modulate cell proliferation and migration in metastatic prostate cancer
Rajina Shakya, Praveen Kumar Suraneni, Amit Rahi, Michael Y. Young, Emily Cousino, Christine B. Magdongon, Raju Gajjela, Basil Baby Mattamana, Alexander Zaslavsky, Ganesh S. Palapattu, Arun Sreekumar, Dileep Varma
This study investigates how GNPNAT1 knockdown in CRPC cells affects cytoskeletal structure, proliferation, and migration through metabolic and signaling pathways.
Cell Communication and Signaling · Mar 28, 2026Peer-reviewedCancer Biology