Deconvolving the structural heterogeneity of alpha-Synuclein in vitro and in situ
Liliana Malinovska, Alexandra Malinovska, Yuehan Feng, Lynn Verbeke, Pratibha Kumari, José D. Camino, Valentina Cappelletti, Sonja Kroschwald, Elisa Dultz, Meltem Tatlı, Walther Haenseler, Tetiana Serdiuk, Alexandra Estermann, Henning Stahlberg, Sally A. Cowley, , Paola Picotti
This paper develops a method to quantitatively analyze the structural states of alpha-synuclein in vitro and in situ, revealing conformational changes in yeast and human neurons.
bioRxiv · May 25, 2026 · PreprintNeuroscience