Potential genetic robustness of Prnp and Sprn double knockout mouse embryos towards ShRNA-lentiviral inoculation
Andréa Rau, Bruno Passet, Johan Castille, Nathalie Daniel-Carlier, Alexandre Asset, Jérôme Lecardonnel, Marco Moroldo, Florence Jaffrézic, Dénis Laloë, Katayoun Moazami‐Goudarzi, Jean-Luc Vilotte
The paper investigates the transcriptomic response of Prnp and Sprn double knockout mouse embryos to ShRNA lentiviral inoculation, finding reduced apoptosis and interferon responses in the double knockout compared to single knockouts.
Veterinary Research · Jul 7, 2022Peer-reviewedGenomics