Florence Jaffrézic

This paper introduces PrP E219K as a new substrate for RT-QuIC that amplifies multiple human prion strains and enables discrimination between sporadic and variant CJD strains.

The paper investigates the transcriptomic response of Prnp and Sprn double knockout mouse embryos to ShRNA lentiviral inoculation, finding reduced apoptosis and interferon responses in the double knockout compared to single knockouts.

This paper introduces padma, a pathway-centric tool that quantifies individualized multi-omic deviations in cancer, correlating them with clinical outcomes in breast and lung cancer.

The paper identifies gene regulatory networks in embryo-endometrium pairs during implantation, revealing coordinated gene expression and functional modules specific to each pregnancy.