Author

Alexej Abyzov

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:ATAC-seq· 1 Approach:deep learning· 1 Approach:machine learning (classical)· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Schahram AkbarianiD· 2 shared Aarti JajooiD· 1 shared Agnieszka KalinowskiiD· 1 shared Ahituv NadaviD· 1 shared Ahyeon HwangiD· 1 shared Aitor Serres· 1 shared Alex A. PolleniD· 1 shared Alex Kozlenkov· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenomics

Schahram AkbarianORCID

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2 papers

Recent·Most cited

Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex

Chengyu Deng, Sean Whalen, Marilyn Steyert, Ryan Ziffra, Pawel F. Przytycki, Fumitaka Inoue, Daniela A. Pereira, Davide Capauto, Scott Norton, Flora M. Vaccarino, Alex A. Pollen, Tomasz Jan Nowakowski, Ahituv Nadav, Katherine S. Pollard, Schahram Akbarian, , Alex Kozlenkov

The paper identifies 46,802 enhancers and 164 psychiatric disorder variants with regulatory effects in the developing cortex and organoids using massively parallel reporter assays and deep learning.

Science · May 23, 2024Peer-reviewedGenomics

Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia

Xiaowei Zhu, Bo Zhou, Reenal Pattni, Kelly Gleason, Chunfeng Tan, Agnieszka Kalinowski, Steven A. Sloan, Anna-Sophie Fiston-Lavier, Jessica Mariani, Dmitri A. Petrov, Ben A. Barres, Laramie E. Duncan, Alexej S. Abyzov, Hannes S. Vogel, Brain Somatic Mosaicism Network, , Gary W. Mathern

The paper introduces a machine learning method to detect somatic L1 insertions in human brain tissue, revealing their widespread distribution in neurons and glia and potential role in neuropsychiatric diseases.

Nature Neuroscience · Jan 11, 2021Peer-reviewedGenomics