Author

Kelly Gleason

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Carol A. TammingaiD· 3 shared Aarthi RamakrishnaniD· 2 shared Amni Al-KachakiD· 2 shared Ashley E. LepackiD· 2 shared Flurin CathomasiD· 2 shared Giuseppina Di SalvoiD· 2 shared Ian S. MazeiD· 2 shared Li SheniD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Carol A. TammingaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex

Sasha L. Fulton, Jaroslav M. Bendl, Giuseppina Di Salvo, John F. Fullard, Amni Al-Kachak, Ashley E. Lepack, Andrew F. Stewart, Sumnima Singh, Wolfram C. Poller, Ryan M. Bastle, Mads E. Hauberg, Amanda K. Fakira, Vishwendra Patel, Min Chen, Romain Durand-de Cuttoli, , Ian S. Maze

The paper identifies ZBTB7A as a key regulator of MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in the orbitofrontal cortex.

Neuron · Jun 13, 2025Peer-reviewedNeuroscience

Tau seeding without tauopathy

Michael LaCroix, Efrosini Artikis, Brian D. Hitt, Joshua D. Beaver, Sandi Jo Estill, Kelly Gleason, Carol A. Tamminga, Bret M. Evers, Charles L. White, Byron W. Caughey, Marc I. Diamond

The paper detects seeding activity of tau assemblies in healthy human brains, suggesting normal physiological tau function that may contribute to disease when disrupted.

Journal of Biological Chemistry · Dec 9, 2023Peer-reviewedNeuroscience

Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior

Amni Al-Kachak, Sasha L. Fulton, Giuseppina Di Salvo, Jennifer C Chan, Lorna A. Farrelly, Ashley E. Lepack, Ryan M. Bastle, Lingchun Kong, Flurin Cathomas, Emily L. Newman, Caroline Ménard, Aarthi Ramakrishnan, Polina Safovich, Yang Lyu, Herbert E. Covington, , Ian S. Maze

The paper investigates how serotonin modifies histone H3K4me3Q5ser dynamics in the dorsal raphe nucleus under stress and antidepressant exposure, showing its role in gene expression and behavior.

bioRxiv · May 4, 2023 · PreprintNeuroscience

Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia

Xiaowei Zhu, Bo Zhou, Reenal Pattni, Kelly Gleason, Chunfeng Tan, Agnieszka Kalinowski, Steven A. Sloan, Anna-Sophie Fiston-Lavier, Jessica Mariani, Dmitri A. Petrov, Ben A. Barres, Laramie E. Duncan, Alexej S. Abyzov, Hannes S. Vogel, Brain Somatic Mosaicism Network, , Gary W. Mathern

The paper introduces a machine learning method to detect somatic L1 insertions in human brain tissue, revealing their widespread distribution in neurons and glia and potential role in neuropsychiatric diseases.

Nature Neuroscience · Jan 11, 2021Peer-reviewedGenomics