Reduced activity of Adenylyl Cyclase 1 Attenuates Morphine Induced Hyperalgesia and Inflammatory Pain in Mice
Kayla Johnson, Alexis Doucette, Alexis Edwards, Aleeya Verdi, Ryan McFarland, Shelby Hulke, Amanda Fowler, Val J. Watts, Amanda H. Klein
This study shows reducing Adenylyl Cyclase 1 activity decreases morphine-induced hyperalgesia and inflammatory pain in mice without affecting morphine's analgesic effects.
Frontiers in Pharmacology · Sep 2, 2022Peer-reviewedNeuroscience