The plasma Factor XIII heterotetrameric complex structure: unexpected unequal pairing within a symmetric complex
Sneha Singh, Alexis Nazabal, Senthilvelrajan Kaniyappan, Jean‐Luc Pellequer, Alisa S. Wolberg, Diana Imhof, Johannes Oldenburg, Arijit Biswas
The paper determines the structure of the FXIII-A2B2 complex, revealing asymmetric subunit pairing critical for its assembly and activation.
Biomolecules · Nov 21, 2019Peer-reviewedMolecular Biology