Senthilvelrajan Kaniyappan

This study shows that Tau condensation, driven by molecular crowding and RNA coacervation, leads to pathological Tau accumulation at the nuclear envelope and affects nucleocytoplasmic transport.

This paper shows that FRET-based Tau seeding assays do not reflect prion-like templated assembly of Tau fibers, as GFP tags inhibit aggregation and alter fiber structure.

The paper determines the structure of the FXIII-A2B2 complex, revealing asymmetric subunit pairing critical for its assembly and activation.