NMDA receptor misalignment in iPSC-derivedneurons from a multi-generational family withinherited Creutzfeldt-Jakob disease
Aldana D. Gojanovich, Nhat T. T. Le, Robert C.C. Mercer, Seonmi Park, Bei Wu, Alice Anane, Janelle S. Vultaggio, Gustavo Mostoslavsky, David A. Harris
This study uses iPSC-derived neurons from a family with the E200K prion mutation to model disease-relevant phenotypes, including PrP accumulations and NMDA receptor misalignment.
Stem Cell Reports · Sep 26, 2024Peer-reviewedNeuroscience