Unique epigenomic signatures identify biologically significant subtypes of MDS and predict response to azacitidine
Qin Yang, Miguel Torres‐Martín, Masataka Taguchi, Alice Brogi, Irene Casalin, Eleonora Ceneri, Stephanie Halene, Amy Elizabeth Dezern, Elizabeth A. Griffiths, Matilde Y. Follo, Carlo Finelli, Jerald P. Radich, Michael J. Rauh, Rafael L. Bejar, Mikkael Aaron Sekeres, , María E. Figueroa
This study identifies epigenetic subtypes of MDS using DNA methylation patterns and develops a predictive signature for azacitidine response.
bioRxiv · Apr 23, 2025 · PreprintCancer Biology