Human Puf-A, a Novel Component of 90S Pre-ribosome, Links Ribosome Biogenesis to Cancer Progression
Huan-Chieh Cho, Yenlin Huang, Jung-Tung Hung, Li-Chun Lai, Sheng-Hung Wang, Yun-Hen Liu, I-Ming Cho, Ming-Wei Kuo, Pei-Yi Cheng, Ming-Yi Ho, Rey-Jin Lin, Alice L. Yu, John Yu
This study identifies Puf-A as a novel 90S pre-ribosome component that links ribosome biogenesis to cancer progression by regulating pre-rRNA structure and tumor growth.
bioRxiv · Mar 13, 2018 · PreprintCancer Biology