Author

John Yu

Cedars-Sinai Medical CenterPrimary ORCID profile (0000-0002-9857-4349 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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John YuiD1 paper

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alice L. Yu· 1 shared Dnyaneshwar Kalyane· 1 shared Hongqiang Wang· 1 shared Huan-Chieh Cho· 1 shared I-Ming Cho· 1 shared Jeremy David RudnickiD· 1 shared Jung-Tung Hung· 1 shared Keerthi Caroline Sadanala· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Alice L. Yu

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2 papers

Recent·Most cited

Ligand stabilization enables physiological GITR signaling and antitumor immunity

Tesfahun Dessale Admasu, Keerthi Caroline Sadanala, Dnyaneshwar Kalyane, Hongqiang Wang, Seokyoung Yoon, Woohyun Kim, Madhusudhanarao Katiki, Jeremy David Rudnick, Ramachandran Murali, John Yu

This study shows that stabilizing the GITRL ligand enhances antitumor immunity by enabling physiological signaling between APCs and T cells, unlike receptor-targeted antibodies.

bioRxiv · May 8, 2026 · PreprintCancer Biology

Human Puf-A, a Novel Component of 90S Pre-ribosome, Links Ribosome Biogenesis to Cancer Progression

Huan-Chieh Cho, Yenlin Huang, Jung-Tung Hung, Li-Chun Lai, Sheng-Hung Wang, Yun-Hen Liu, I-Ming Cho, Ming-Wei Kuo, Pei-Yi Cheng, Ming-Yi Ho, Rey-Jin Lin, Alice L. Yu, John Yu

This study identifies Puf-A as a novel 90S pre-ribosome component that links ribosome biogenesis to cancer progression by regulating pre-rRNA structure and tumor growth.

bioRxiv · Mar 13, 2018 · PreprintCancer Biology