Cryptic leukemia antigens share homology with microbial epitopes and stimulate T-cell responses in healthy donors
Caroline Rulleau, Marie‐France Aubin, Gabrielle Boudreau, Alice Loiselle, Ann Brasey, Ali Smaani, Cédric Carli, Marie‐Pierre Hardy, Lambert Busque, Claude Perreault, Benjamin Haley, Assya Trofimov, Jean‐Sébastien Delisle
The paper identifies cryptic leukemia antigens that share homology with microbial epitopes and can stimulate T-cell responses in healthy donors, suggesting their potential as targets for T-cell-based immunotherapies.
bioRxiv · Dec 2, 2025 · PreprintImmunology