E2F/Dp inactivation in fat body cells triggers systemic metabolic changes
María Paula Zappia, Ana Guarner, Nadia Kellie-Smith, Alice Rogers, Robert Tyler Morris, Brandon Nicolay, Myriam Boukhali, Wilhelm Haas, Nicholas J. Dyson, Maxim V. Frolov
This study shows that E2F inactivation in fat body cells causes systemic metabolic changes, including reduced trehalose and fat storage, which can be rescued by sugar supplementation.
eLife · Jul 12, 2021Peer-reviewedDevelopmental Biology