María Paula Zappia

This study shows that Arginine kinase 1 is essential for energy homeostasis during Drosophila muscle development, affecting myofibrillogenesis, muscle growth, and function.

This study shows that medium-chain fatty acid exposure in non-transformed mammary glands induces aging-like changes linked to breast cancer risk.

The paper shows that lipid metabolism, specifically through OA, shifts metabolic pathways in breast cells, increasing SAM and 2-HG, which contribute to oncogenic properties and epigenetic changes.

This study shows that activating the GeneSwitch system in adult Drosophila muscles with RU486 causes severe structural and lifespan defects, highlighting the need for careful experimental design.

This study shows that E2F binding to the metabolic gene Pgk affects glycolytic flux, mitochondrial morphology, and lifespan in Drosophila.

This study shows that E2F inactivation in fat body cells causes systemic metabolic changes, including reduced trehalose and fat storage, which can be rescued by sugar supplementation.

The paper constructs a single-cell RNA-seq atlas of Drosophila muscle precursors to identify transcriptional signatures and a novel gene involved in muscle divergence.