Author

Alice Zhang

Buck Institute for Research on Aging

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Biology Disciplines

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Douglas R. SealsiD· 1 shared Edgard Morazan· 1 shared James Galligan· 1 shared Katelyn R. LudwigiD· 1 shared Kiyomi Raye KaneshiroiD· 1 shared Lauren A. WimeriD· 1 shared Lizbeth Enriquez Najera· 1 shared Marrisa Trujillo· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Douglas R. SealsORCID

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1 paper

Recent·Most cited

Methylglyoxal-induced glycation stress promotes aortic stiffening: Putative mechanistic roles of oxidative stress and cellular senescence

Parminder Singh, Ravinandan Venkatasubramanian, Sophia A. Mahoney, Mary A. Darrah, Katelyn R. Ludwig, Alice Zhang, Kiyomi Raye Kaneshiro, Lizbeth Enriquez Najera, Lauren A. Wimer, Muniesh Muthaiyan Shanmugam, Edgard Morazan, Marrisa Trujillo, James Galligan, Richmond Sarpong, Douglas R. Seals, , Zachary Stephen Clayton

This study shows that methylglyoxal-induced glycation stress causes aortic stiffening through oxidative stress and cellular senescence, and a glycation-lowering compound mitigates these effects.

Aging · Nov 14, 2025Peer-reviewedMolecular Biology