Molecular BiologyAgingPeer-reviewed
Methylglyoxal-induced glycation stress promotes aortic stiffening: Putative mechanistic roles of oxidative stress and cellular senescence
Parminder Singh, Ravinandan Venkatasubramanian, Sophia A. Mahoney…·Zachary Stephen Clayton
This study shows that methylglyoxal-induced glycation stress causes aortic stiffening through oxidative stress and cellular senescence, and a glycation-lowering compound mitigates these effects.
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