Author

Alisa Sedghifar

Princeton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Yaniv Brandvain· 2 shared Aaron A. Comeault· 1 shared Benjamin M. MoraniD· 1 shared Brandon S. Cooper· 1 shared Catherine A. Ball· 1 shared Daniel L. PowelliD· 1 shared Daniel R. Matute· 1 shared David A. TurissiniiD· 1 shared

Activity by Year

2015-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersGenetics

Yaniv Brandvain

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5 papers

Recent·Most cited

Admixture mapping reveals evidence for multiple mitonuclear incompatibilities in swordtail fish hybrids

Nemo V. Robles, Benjamin M. Moran, María José Rodríguez-Barrera, Gaston I. Jofre, Theresa Rose Gunn, Erik N. K. Iverson, Sofia G. Beskid, John James Baczenas, Alisa Sedghifar, Peter Andolfatto, Daniel L. Powell, Yaniv J Brandvain, Justin C. Havird, Gil Guastoni Rosenthal, Molly E. Schumer

The paper uses admixture mapping in swordtail fish hybrids to identify mitonuclear incompatibilities, finding nine genomic regions involved in interactions between nuclear and mitochondrial genomes.

Molecular Ecology · Sep 16, 2025Peer-reviewedEvolutionary Biology

Ancestry Inference Using Reference Labeled Clusters of Haplotypes

Yong Wang, Shiya Song, Joshua G. Schraiber, Alisa Sedghifar, Jake Byrnes, David A. Turissini, Eurie L. Hong, Catherine A. Ball, Keith Noto

ARCHes infers ancestry composition using haplotype-based models, outperforming RFMix in global and local ancestry assignment across diverse populations.

BMC Bioinformatics · Sep 25, 2021Peer-reviewedGenomics

A Maladaptive Combination Of Traits Contributes To The Maintenance Of A Stable Hybrid Zone Between Two Divergent Species Of Drosophila

Brandon S. Cooper, Alisa Sedghifar, W. Thurston Nash, Aaron A. Comeault, Daniel R. Matute

The paper identifies a stable hybrid zone between Drosophila yakuba and D. teissieri, showing that maladaptive trait combinations and hybrid male sterility limit gene flow.

bioRxiv · May 16, 2017 · PreprintEvolutionary Biology

Beyond clines: lineages and haplotype blocks in hybrid zones

Alisa Sedghifar, Yaniv Brandvain, Peter Ralph

The paper studies how selection against hybrid genotypes affects introgression patterns in hybrid zones, showing how clines form and how parental haplotypes are disrupted.

bioRxiv · Apr 27, 2016Genetics

The Spatial Mixing of Genomes in Secondary Contact Zones

Alisa Sedghifar, Yaniv Brandvain, Peter L. Ralph, Graham Coop

The paper develops a theoretical framework to infer the age of geographic contact zones using population genomic data and applies it to human populations in Indonesia, Central Asia, and India.

Genetics · Jul 22, 2015Peer-reviewedEvolutionary Biology