Cancer BiologyCell Communication and SignalingPeer-reviewed
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Adviti Naik, Remy Thomas, Aljazi Al-Khalifa…·Julie V. Decock
This study investigates how tumor LDHC expression affects immune responses in breast cancer, finding that LDHC knockdown enhances T cell activation and reduces immunosuppressive factors and checkpoint molecule expression.
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