Langerhans Cells Regulate Tongue Intraepithelial Innervation in a Microbiota- and Age-Dependent Manner
Yasmin Netanely, Yasmin Saba, Reem Naamneh, Shahd Yacoub, Yasmin Jaber, Alon Raviv, Luba Eli‐Berchoer, Hagit Shapiro, Eran Elinav, Asaf Wilensky, Björn E. Clausen, Avi‐Hai Hovav
This study shows oral Langerhans cells regulate tongue innervation via IL-1β and NGF, with microbiota and age affecting this neuroimmune function.
bioRxiv · Apr 3, 2025 · PreprintImmunology