Björn E. Clausen

This study shows that E-cadherin in oral Langerhans cells maintains dendritic morphology and microbiota-dependent immune homeostasis, preventing dysbiosis and inflammation.

This study shows B cells sustain Langerin+ cDC1s via LTβ and MMMs to support anti-viral CD8+ T cell responses during MCMV infection.

This study shows glycosylated GM-CSF expands immunosuppressive B-1b plasma cells and promotes regulatory functions, while non-glycosylated GM-CSF drives pro-inflammatory responses.

This study shows oral Langerhans cells regulate tongue innervation via IL-1β and NGF, with microbiota and age affecting this neuroimmune function.

The paper identifies RORγt-expressing dendritic cells as a distinct APC lineage conserved across tissues and species, with functions beyond promoting tolerance.