Local translational program at the muscle-tendon junction endows domain identity in muscle syncytia
Juliana de Carvalho Neves, Nour El Khazen, Coalesco Smith, Vedran Franke, Sakulrat Mankhong, Edgar Jauliac, Laura Yedigaryan, Elise Lefebvre, Altuna Akalins, Pascal Maire, Minchul Kim
The paper identifies local translational regulation at the muscle-tendon junction (MTJ) and shows that KLF-family transcription factors are translationally upregulated there, driving domain-specific gene expression.
bioRxiv · Jan 2, 2026 · PreprintCell Biology