Identifying cytokine-release signatures of flow-driven endothelial remodelling in an intracranial aneurysm cell culture model
Chloe M. de Nys, Tiago Guerzet Sardenberg Lima, Haveena Anbananthan, Timothy Mitchell, Salma Mansi, Alyssa Binder, Zhiyong Li, James I. Novak, Petra Mela, Steven G. Wise, Danilo Carluccio, Craig D. Winter, Ashley R. Murphy, Rose Ann Franco, Mark C. Allenby
This study develops an in vitro intracranial aneurysm model with cardiovascular flow to investigate endothelial remodelling and identifies cytokine signatures as potential biomarkers for IA remodelling.
bioRxiv · Jun 20, 2026 · PreprintBioengineering