Mark C. Allenby

This study develops marrow-mimic scaffolds that enhance cRBC production by supporting macrophage-erythroblast interactions in high-density cultures.

This paper presents a microfluidic system to create spatial growth factor gradients in hydrogels for studying CD34+ cell behavior and optimizing culture conditions.

This paper develops a thermodynamic continuum model of tumour spheroid growth that recovers multicompartment structure and supports drug-response screening without prescribing compartments.

This study develops an in vitro intracranial aneurysm model with cardiovascular flow to investigate endothelial remodelling and identifies cytokine signatures as potential biomarkers for IA remodelling.

This paper develops patient-specific intracranial aneurysm models using additive manufacturing to study pathophysiology and rupture risk.

This study uses fluid-structure interaction simulations to evaluate how graft material, suture material, and anastomosis angle affect blood flow and shear stress in vascular grafts.

This study introduces a biomechanics-histology FEA framework to simulate BigMACS and derive mechanobiology design relationships for controlling cell behavior and tissue patterning.

BRAT is a tool for high-content microscopy screening of microvascular networks, offering fast and accurate analysis of vascular images.

This paper develops a microfluidic co-culture system that enables the reproducible formation of vascularised adipose tissue from immortalised cells, showing that vascular networks significantly enhance adipocyte differentiation.

This study uses spatial transcriptomics to identify placental dysfunction signatures in SARS-CoV-2 infected pregnancies, revealing altered gene expression related to hypoxia, oxidative stress, and preeclampsia-like pathways.

This paper introduces an automated method to detect unruptured intracranial aneurysms in MRAs using single-voxel morphometry with high specificity and sensitivity.