Surviving phage attack primes bacterial immunity to defeat counterdefenses
Reid T. Oshiro, Alyssa Pratt, Drew T. Dunham, Lindsey Doyle, Clare Gill, Ani Chouldjian, Kerilyn Higashi, Julieta Peralta Acosta, Sydney McGuire, Sam Nouwens, Brett K. Kaiser, Kimberley D. Seed
The paper shows that restricted phage infection primes bacterial immunity to defeat counterdefenses by increasing defense protein abundance and altering host-phage stoichiometry.
bioRxiv · Nov 13, 2025 · PreprintMicrobiology