Human PMS1-dependent non-canonical mismatch repair converges with MBD4 to repair 5-methylcytosine deamination
Anaïs Le Ven, Sandra Vanhuele, Olivier Ganier, Alexandre Houy, Amanda Kahn, Manuel Jorge Rodrigues, Marc‐Henri Stern, Raphaël Guérois, André Bortolini Silveira
The paper shows that MBD4 and PMS1-dependent non-canonical MMR work together to repair 5mC deamination, contributing to genome stability.
bioRxiv · Jan 17, 2026 · PreprintMolecular Biology