Molecular Determinants of G Protein Subtype-Specific Coupling to the Angiotensin II Type 1 Receptor
Akua Acheampong, Matthew K. Collins, Amanda R. Keller, Andrew P. Feld, Brandi M. Small, Michael Ritt, Carl‐Mikael Suomivuori, Sivaraj Sivaramakrishnan, Laura M. Wingler
This study identifies molecular determinants in the 5 helix of the AT1R that govern subtype-specific coupling to Gq and Gi proteins.
bioRxiv · Oct 2, 2026 · PreprintBiochemistry