Author

Carl‐Mikael Suomivuori

Yale UniversityORCID 0000-0002-2445-8791Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Ron O. DroriD· 2 shared Adrian NegreaniD· 1 shared Akua AcheampongiD· 1 shared Alem W. KahsaiiD· 1 shared Ali MasoudiiD· 1 shared Amanda R. Keller· 1 shared Andrew P. FeldiD· 1 shared Angus Li· 1 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

Ron O. DrorORCID

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Author profile →

4 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 2, 2026

Molecular Determinants of G Protein Subtype-Specific Coupling to the Angiotensin II Type 1 Receptor

Akua Acheampong, Matthew K. Collins, Amanda R. Keller…·Laura M. Wingler

This study identifies molecular determinants in the 5 helix of the AT1R that govern subtype-specific coupling to Gq and Gi proteins.

DOI 10.64898/2026.09.30.755740

humanproteomics

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BiophysicsNature CommunicationsPeer-reviewedSep 28, 2026

Structural basis of stepwise G protein activation by the viral chemokine receptor US28

Kevin M. Jude, Carl‐Mikael Suomivuori, Deepa Waghray…·Naotaka Tsutsumi

The paper determines structural states of the US28-Gq complex to elucidate a stepwise G protein activation mechanism.

DOI 10.1038/s41467-026-78122-7

experimental assay

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BiochemistrybioRxivPreprintJul 16, 2026

Conformational Basis of Functionally Selective Allosteric Modulation of the Angiotensin II type 1 Receptor by Small Molecules

Samuel Liu, Peng Xiao, Matthias Elgeti…·Robert J. Lefkowitz

The paper identifies and characterizes small molecule allosteric modulators of the AT1R, revealing their conformational mechanisms and effects on G protein and β-arrestin pathways.

DOI 10.64898/2026.07.15.736838

experimental assaydrug response / drug discovery

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NeuroscienceNature MethodsPeer-reviewedJul 1, 2023

A positively tuned voltage indicator reveals electrical correlates of calcium activity in the brain

Stephen W. Evans, Dongqing Shi, Mariya Chavarha…·Michael Z. Lin

This paper introduces positively tuned GEVIs that enhance spike detection in vivo with standard imaging systems, offering higher temporal resolution than calcium indicators.

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imagingexperimental assay

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